Several smaller drug and biotech companies are due to report their earnings this week. Almost all big drugmakers have already reported their results. The fourth-quarter earnings season was a mixed bag for these large drug/biotech companies. While Lilly, Gilead, AstraZeneca, Regeneron and J&J beat estimates for both earnings and sales, Merck, Sanofi and Novartis missed on both counts. Others like Pfizer, Biogen and Glaxo missed estimates for earnings while beating the same for sales.Per the Zacks classification, the pharma/biotech industry comes under the broader Medical sector, which comprises pharma/biotech as well as medical device companies.Per the Earnings Trends report as of Feb 17, 85.5% of the companies in the Medical sector, constituting nearly 93.5% of the sector’s market capitalization, reported earnings. While 78.7% beat earnings estimates, 85.1% beat the same for sales. Earnings increased 16.8% year over year on 13.3% higher revenues. Overall, fourth-quarter earnings for the Medical sector are expected to rise 14.6% on 12.9% sales increase.Let’s analyze the five drug/biotech companies that are set to report fourth-quarter 2020 results on Feb 23.Jazz Pharmaceuticals JAZZJazz Pharmaceuticals has a mixed earnings track record. It surpassed earnings estimates thrice in the past four quarters while missing in one, recording an average negative earnings surprise of 2.22%.Jazz Pharmaceuticals PLC Price and EPS Surprise Jazz Pharmaceuticals PLC price-eps-surprise | Jazz Pharmaceuticals PLC QuoteJazz has an Earnings ESP of +1.00% and a Zacks Rank #5 (Sell).The Zacks Consensus Estimate for earnings stands at $4.10 per share.Per our proven model, stocks with the combination of a positive Earnings ESP and a Zacks Rank #1 (Strong Buy), #2 (Buy) or #3 (Hold) have a good chance of delivering earnings beat. You can uncover the best stocks to buy or sell before they’re reported with our Earnings ESP Filter.Arena Pharmaceuticals ARNAThe biotech’s earnings beat the Zacks Consensus Estimate in three of the last four quarters with the average surprise being 9.36%.Arena Pharmaceuticals, Inc. Price and EPS Surprise Arena Pharmaceuticals, Inc. price-eps-surprise | Arena Pharmaceuticals, Inc. QuoteThis #3 Ranked company has an Earnings ESP of 0.00%. The Zacks Consensus Estimate for loss stands at $1.97 per share per share.Esperion Therapeutics ESPRThe company surpassed expectations in the trailing four quarters by 35.44%, on average.Esperion Therapeutics, Inc. Price and EPS Surprise Esperion Therapeutics, Inc. price-eps-surprise | Esperion Therapeutics, Inc. QuoteEsperion has an Earnings ESP of -7.12% and a Zacks Rank #3. You can see the complete list of today’s Zacks #1 Rank stocks here.The Zacks Consensus Estimate for loss stands at $3.76 per share.Epizyme EPZMThe company has a mixed track record. It missed earnings expectations twice in the last four quarters and beat the same on the other two occasions. The average earnings surprise was 5.42%Epizyme, Inc. Price and EPS Surprise Epizyme, Inc. price-eps-surprise | Epizyme, Inc. QuoteEpizyme has an Earnings ESP of 0.00% and it carries a Zacks Rank #3.The Zacks Consensus Estimate for loss stands at 59 cents per share.Halozyme Therapeutics HALOThe biotech’s earnings missed the Zacks Consensus Estimate in three of the last four quarters with the average negative surprise being 83.08%.Halozyme Therapeutics, Inc. Price and EPS Surprise Halozyme Therapeutics, Inc. price-eps-surprise | Halozyme Therapeutics, Inc. QuoteThis #3 Ranked company has an Earnings ESP of -5.92%. The Zacks Consensus Estimate for earnings stands at 56 cents per share per share.5 Stocks Set to DoubleEach was hand-picked by a Zacks expert as the #1 favorite stock to gain +100% or more in 2020. Each comes from a different sector and has unique qualities and catalysts that could fuel exceptional growth.Most of the stocks in this report are flying under Wall Street radar, which provides a great opportunity to get in on the ground floor.Today, See These 5 Potential Home Runs >>Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Arena Pharmaceuticals, Inc. (ARNA): Free Stock Analysis Report Jazz Pharmaceuticals PLC (JAZZ): Get Free Report Halozyme Therapeutics, Inc. (HALO): Free Stock Analysis Report Esperion Therapeutics, Inc. (ESPR): Free Stock Analysis Report Epizyme, Inc. (EPZM): Get Free Report To read this article on Zacks.com click here. Zacks Investment Research