What happened Shares of Ardelyx (NASDAQ: ARDX) were soaring 8.9% as of 2:57 p.m. EDT on Wednesday. The big jump came after the company announced that its Japanese partner, Kyowa Kirin, has begun four late-stage clinical studies evaluating Ardelyx's lead candidate tenapanor in treating hyperphosphatemia, a disorder where there's an abnormally high level of phosphate in the blood. So what Kyowa Kirin's initiation of multiple phase 3 studies is good news for Ardelyx in a couple of ways. For one thing, it triggered a $5 million milestone payment. More importantly, it gets the two collaboration partners even closer to potential regulatory approval for tenapanor in Japan. Image source: Getty Images. Ardelyx received a $30 million up-front payment from Kyowa Kirin in 2017 when the Japanese drugmaker licensed tenapanor, and it stands to receive a total of up to $55 million in development milestone payments plus up to 8.5 billion yen (around $78 million based on current exchange rates) in commercialization milestones. Ardelyx will also receive royalties in the high teens if tenapanor wins approval in Japan. Now what While the start of Japanese clinical studies is good news for Ardelyx, a more important milestone for the biotech stock is only a couple of weeks away. By April 29, the Food and Drug Administration should announce its approval decision for tenapanor in controlling phosphorus levels in adult patients with chronic kidney disease. 10 stocks we like better than ArdelyxWhen investing geniuses David and Tom Gardner have a stock tip, it can pay to listen. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.* David and Tom just revealed what they believe are the ten best stocks for investors to buy right now... and Ardelyx wasn't one of them! That's right -- they think these 10 stocks are even better buys. See the 10 stocks *Stock Advisor returns as of February 24, 2021 Keith Speights has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.Source