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NantBioScience and NantKwest Partner with the National Cancer Institute to Further Develop Recombinant NK Cells and Monoclonal Antibodies as Monotherapies and Combination Cancer Immunotherapies

CULVER CITY, Calif.--(BUSINESS WIRE)--NantBioScience, Inc., is a biopharmaceutical company focused on the discovery of innovative treatments by developing molecularly targeted drugs, based on the molecular profile of the patient’s tumor, independent of the cancer’s anatomical type. NantKwest, Inc. (Nasdaq: NK), an affiliate of NantBioScience, is a clinical-stage immunotherapy company focused on harnessing the power of the innate immune system by using natural killer cells to treat cancer, infectious diseases and inflammatory diseases. NantBioScience announced today that it has entered into a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute (NCI), an Institute of the National Institutes of Health (NIH). Under the CRADA, NantBioScience and its affiliates, such as NantKwest, will work together to further develop their proprietary recombinant NK and monoclonal antibodies in monotherapy and in combination immunotherapies.

“We look forward to combining our expertise with those at the NCI to create a multi-pronged paradigm-shifting immunotherapeutic attack of cancer”

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NantBioScience and NantKwest will be working with Dr. Jeffrey Schlom, Chief of the Laboratory of Tumor Immunology and Biology, NCI, and Dr. James Gulley, Chief of the Genitourinary Malignancies Branch, NCI, and their teams to expand the preclinical and clinical development of recombinant NK cells and monoclonal antibodies, for use in combinations with other immunotherapeutics, such as vaccines and immune modulators, and other forms of cancer therapy. Both in vitro and in vivo preclinical testing will be conducted to further develop NantBioScience’s and NantKwest’s proprietary agents, and Phase I and II clinical studies will be carried out both at the NIH Clinical Center and in collaboration with investigators at extramural Cancer Centers.

“We look forward to combining our expertise with those at the NCI to create a multi-pronged paradigm-shifting immunotherapeutic attack of cancer,” said Patrick Soon-Shiong, MD, Chief Executive Officer, NantBioScience and NantKwest. “The worlds of genomics, proteomics, immunology, and immunotherapy have advanced and converged at an unprecedented speed. The studies conducted as part...


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