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Entry into a Material Definitive Agreement

Lease Agreement Amendment

On April7, 2016, Achillion Pharmaceuticals, Inc. (the Company) entered into Amendment No.4 (the Lease Amendment) of its facility Lease Agreement, dated March6, 2002, as previously amended by Amendment No.1, dated September10, 2002, Amendment No.2, dated March31, 2010, and Amendment No. 3, dated August20, 2015 between the Company and WE George Street, L.L.C. (the Landlord) for the leased premises at 300 George Street, New Haven, Connecticut (the 300 George Street Lease). Pursuant to the Lease Amendment, effective as of April15, 2016 (the Second Expansion Commencement Date), the Company will lease an additional 2,877 rentable square feet of space...


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