- Seasonal influenza nanoparticle approach replaces VLP program
- HHS BARDA contract will complete its term as scheduled in September 2016
- Nanoparticle design builds on advances achieved with RSV F Vaccine
- Animal immunogenicity and efficacy data demonstrate broadly neutralizing antibodies
- Data presented at Keystone Symposia
GAITHERSBURG, Md., June 02, 2016 (GLOBE NEWSWIRE) -- Novavax, Inc., (
Data included in the presentation demonstrate Novavax’ progress in developing seasonal influenza nanoparticles that are protective in a ferret influenza challenge model when combined with our proprietary adjuvant, Matrix-M™. The vaccine candidate is based on a hemagglutinin nanoparticle and elicited broadly neutralizing antibodies to all three types of influenza viruses: A(H3N2), A(H1N1), and B, with specificity to both contemporary and historical influenza strains.
The presentation can be accessed at:
Nanoparticle Design Builds on Advances Achieved with RSV F Vaccine
“Our seasonal influenza nanoparticle approach builds on the advances achieved with our RSV nanoparticle. Our breakthrough in RSV vaccine development leverages conserved sites within the F protein to provide protection from contemporary and historical strains of RSV. We have replicated that approach in developing our seasonal influenza nanoparticle. Novavax pioneered the use of palivizumab-competing antibodies as a metric for an effective immune response to RSV and we have developed a similar, influenza-specific, broadly neutralizing monoclonal antibody competition assay to test responses to our new influenza vaccine,” said Gregory Glenn M.D., President of Research and Development. “Our seasonal...