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Trading the five stocks that have risen more than 50% this year

Five stocks in the S&P 500 have risen by more than 50 percent this year: Vertex Pharmaceuticals, Activision Blizzard, Align Technology, CSX and Wynn Resorts.

Which one has the best shot at continuing its rally through the rest of the year?

Chad Morganlander, portfolio manager at Washington Crossing Advisors, would put his money on shares of CSX. The rail company's stock that is up 53 percent this year on impressive earnings as well as on optimism surrounding the appointment of respected railroad executive Hunter Harrison as CEO.

"We are encouraged by the consistent free cash flow and sturdy...