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Prospectuses and communications, business combinations

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Filed by Anthem, Inc.

(Commission File No. 001-16751) pursuant

to Rule 425 under the Securities Act of

1933 and deemed filed pursuant to

Rule 14a-6(b) under the Securities Exchange

Act of 1934

Subject Company: Cigna Corporation

Commission File No. 001-08323

Commission File No. for Registration Statement on

Form S-4 filed by Anthem, Inc.: 333-207218

ISS RECOMMENDS ANTHEM SHAREHOLDERS VOTE FOR

ACQUISITION OF CIGNA

Indianapolis, Ind. Nov. 16, 2015 Anthem, Inc. (NYSE: ANTM) announced today that Institutional Shareholder Services (ISS), a leading independent proxy advisory firm, has issued a report recommending that Anthem shareholders vote to approve the issuance of Anthem stock in the proposed acquisition of Cigna Corporation (NYSE: CI) at the companys special meeting of shareholders to be held on Thursday, December 3, 2015.

We are pleased that ISS has closely studied the merits of Anthems acquisition of Cigna and urged shareholders to support this compelling combination, said Joseph R. Swedish, President and Chief Executive Officer, Anthem. The Anthem and Cigna businesses are highly complementary with very limited overlap in the geographies and market segments in which we operate. Together, Anthem and Cigna will be better able to deliver near- and long-term value by increasing access to high quality, affordable healthcare, enhancing collaboration with providers to focus on patient outcomes, accelerating innovation, and from an overall perspective, helping to meet the challenges of the unprecedented transformation in healthcare.

Anthems board of directors unanimously recommends that Anthem shareholders vote FOR the proposal to issue Anthem common stock to acquire Cigna, which is necessary to complete the transaction.

Anthems special meeting of shareholders is scheduled to take place on Thursday, December 3, 2015, at 8:00 a.m. Eastern Standard Time (EST). The meeting will be held at the Conrad Hotel at 50 W. Washington St., Indianapolis, Ind. Anthem shareholders of record at the close of business on October 22, 2015 will be entitled to vote at the special meeting.

About Anthem, Inc.

Anthem is working to transform health care with trusted and caring solutions. Our health plan companies deliver quality products and services that give their members access to the care they need. With over 72 million people served by its affiliated companies, including more than 38 million enrolled in its family of health plans, Anthem is one of the nations leading health benefits companies. For more information about Anthems family of companies, please visit www.antheminc.com/companies .

IMPORTANT INFORMATION FOR INVESTORS AND SHAREHOLDERS

NO OFFER OR SOLICITATION

This communication does not constitute an offer to sell or a solicitation of an offer to sell or a solicitation of an offer to buy any securities or a solicitation of any vote or approval, nor shall there be any sale of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended, and otherwise in accordance with applicable law.

ADDITIONAL INFORMATION AND WHERE TO FIND IT

The proposed transaction between Anthem, Inc. (Anthem) and Cigna Corporation (Cigna) will be submitted to Anthems and Cignas shareholders for their consideration. In connection with the transaction, Anthem has filed with the U.S. Securities and Exchange Commission (the SEC) a registration statement on Form S-4, including Amendment No. 1 thereto, containing a joint proxy statement of Anthem and Cigna that also constitutes a prospectus of Anthem. The registration statement was declared effective by the SEC on October 26, 2015. Each of Anthem and Cigna commenced mailing the definitive joint proxy statement/prospectus to its shareholders on or about October 28, 2015. This communication is not a substitute for the registration statement, definitive joint proxy statement/prospectus or any other document that Anthem and/or Cigna have filed or may file with the SEC in connection with the proposed transaction.

INVESTORS AND SECURITY HOLDERS OF ANTHEM AND CIGNA ARE URGED TO READ THE DEFINITIVE JOINT PROXY STATEMENT/PROSPECTUS AND OTHER DOCUMENTS FILED WITH...


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