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Financial Statements and

(d)Exhibits

Exhibit

No.

Description

10.1

Amended and Restated Facility Agreement, dated as of October 29, 2015, among Parent, the Borrower, POZEN, Tribute and the Lenders.

10.2

Amended and Restated Registration Rights Agreement, dated as of October29, 2015 among Parent and the Lenders.

Offer or Solicitation

This communication is not intended to and does not constitute an offer to sell or the solicitation of an offer to subscribe for or buy or an invitation to purchase or subscribe for any securities or the solicitation of any vote or approval in any jurisdiction pursuant t o the acquisition or otherwise, nor shall there be any sale, issuance or transfer of securities in any jurisdiction in contravention of applicable law. No offer of securities shall be made except by means of a prospectus meeting the requirements of Section10 of the Securities Act.

Additional Information

In connection with the proposed combination transaction, Aralez has filed with the SEC a registration statement on FormS-4 that includes the joint proxy statement/prospectus of Parent and POZEN that also constitutes a prospectus of Parent. POZEN plans to mail the joint proxy statement/prospectus to its stockholders in connection with the transaction. INVESTORS ARE URGED TO READ THE JOINT PROXY STATEMENT/PROSPECTUS WHEN IT BECOMES AVAILABLE BECAUSE IT WILL CONTAIN IMPORTANT INFORMATION. POZEN stockholders will be able to obtain the joint proxy statement/prospectus, as well as other filings containing information about POZEN and Parent, free of charge, at the website maintained by the SEC at www.sec.gov. POZEN stockholders may also obtain these documents, free of charge, from POZENs website (www.POZEN.com) under the heading InvestorsSEC Filings or by directing a request to made to POZEN at POZEN Inc., 1414 Raleigh Road, Suite400, Chapel Hill, North Carolina 27517.

3

Participants in the Solicitation

The directors and executive officers of Parent and POZEN and other persons may be deemed to be participants in the solicitation of proxies in respect of the transactions contemplated by the joint proxy statement/prospectus. Information regarding POZENs directors and executive officers is available in its definitive proxy statement filed with the SEC by POZEN on April27, 2015. This document can be obtained free of charge from the sources indicated above. Other information regarding the interests of the participants in the proxy solicitation will be included in the joint proxy statement/prospectus and other relevant materials to be filed with the SEC when they become available.

Caution Regarding Forward-Looking Information and Safe Harbor Statement

To the extent any statements made in this document or the presentation contain information that is not...


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