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CRISPR Therapeutics and Casebia Therapeutics Announce Commercial License Agreement With MaxCyte

BASEL, Switzerland, CAMBRIDGE, Mass., and GAITHERSBURG, Md., March 14, 2017 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, and Casebia Therapeutics, a joint-venture established by CRISPR Therapeutics and Bayer AG for developing CRISPR-based therapeutics in select disease areas, today announced they have signed a joint commercial license agreement with MaxCyte, Inc., a US-based global company dedicated to accelerating the discovery, development, manufacturing and commercialization of next-generation, cell-based medicines.

The commercial license builds on an existing research and clinical licensing agreement for select disease areas. Under the terms of the license, CRISPR Therapeutics and Casebia will obtain non-exclusive commercial-use rights to MaxCyte’s cell engineering platform to develop CRISPR/Cas9-based therapies for hemoglobin-related diseases and severe combined immunodeficiency (SCID). MaxCyte will supply its systems to CRISPR Therapeutics and Casebia as part of the license agreement and will receive upfront, milestone, and sales-based payments.

“As we advance CRISPR Therapeutics’ lead programs in hemoglobinopathies to the clinic, it is important we prepare for the future by securing our access to the leading ex vivo delivery solution for both clinical and commercial use,” said Samarth Kulkarni, Chief Business Officer of CRISPR Therapeutics.

MaxCyte’s Flow Electroporation™ Technology enables the transfection of a variety of cell types at very high efficiency while maintaining very high viability. CRISPR Therapeutics and Casebia’s lead programs rely on ex vivo gene editing, where the CRISPR components are delivered to hematopoietic stem cells using the MaxCyte technology.

“With Casebia and CRISPR Therapeutics working closely together, we hope to make bold investments and accelerate our efforts to access and acquire all the leading platform technologies necessary to develop and commercialize CRISPR-based therapeutics,” said Jim Burns, President and CEO of Casebia.

“The initiation of this commercial license agreement with CRISPR Therapeutics and Casebia, both leaders in gene editing, marks a very important milestone for MaxCyte and demonstrates the value of our platform and our intellectual property, as well as...