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Actionable news in VRTX: Vertex Pharmaceuticals Incorporated,

S&P 500, Nasdaq poised for new closing highs

The S&P 500 and Nasdaq (^DJI, ^GSPC, ^IXIC) are poised for new closing highs, as earnings season rolls on. Catch The Final Round at 4 p.m. with Jen Rogers and Yahoo Finance Editor-in-Chief Andy Serwer.

Winners and losers

Stocks in the red today include railroad operator CSX despite an earnings beat, as its forward guidance disappointed; IBM as revenue declined for the 21st consecutive quarter while profit margins...