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Entry into a Material Definitive

Celgene Corporation (the Company) entered into an amendment dated April 18, 2016 (the Amendment) to the Second Amended and Restated Credit Agreement (the Credit Agreement), dated April17, 2015, with the financial institutions parties thereto (the Lenders), and Citibank, N.A., as administrative agent for the Lenders.

Among other things, the Amendment (i) modifies the Companys existing senior unsecured revolving credit facility, which is governed by the Credit Agreement, byextending the term of the credit facility to April17, 2021 from April 17, 2020, and (ii)confirms the increase in the amount of the Lenders total credit commitment under the credit facility to $2.0 billion from $1.75...