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Shire Quarterly Profit Tops Estimates as Drug Sales Soar

Shire Plc reported first-quarter earnings that beat analysts’ estimates as sales climbed for its key ADHD drug and medicines to treat rare diseases obtained in last year’s acquisition of NPS Pharmaceuticals Inc.

Earnings per American depositary shares rose to $3.19, the Dublin-based company said in a statement on Friday. That compared with the $3.05 average of 15 analysts’ estimates compiled by Bloomberg. Sales grew 15 percent to $1.71 billion.

Sales of Vyvanse, used to treat attention deficit hyperactivity disorder...